{{Rsnum
|rsid=735396
|Gene=HNF1A
|Chromosome=12
|position=121001041
|Orientation=minus
|GMAF=0.3673
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=HNF1A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 36.3 | 51.3 | 12.4
| HCB | 24.8 | 55.5 | 19.7
| JPT | 11.5 | 52.2 | 36.3
| YRI | 84.4 | 14.3 | 1.4
| ASW | 66.7 | 31.6 | 1.8
| CHB | 24.8 | 55.5 | 19.7
| CHD | 32.1 | 46.8 | 21.1
| GIH | 30.7 | 41.6 | 27.7
| LWK | 67.3 | 30.0 | 2.7
| MEX | 46.6 | 37.9 | 15.5
| MKK | 46.8 | 46.8 | 6.4
| TSI | 34.3 | 50.0 | 15.7
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs735396
|Name_s=
|Gene_s=C12orf43, HNF1A
|Feature=
|Evidence=PubMed ID:18439552
|Annotation=In a GWAS of subjects from the PARC study (Pharmacogenomics and Risk of Cardiovascular Disease), this was one of the ten SNPs most strongly associated with plasma C-reactive protein levels.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA162399732
}}

{{PMID Auto GWAS
|PMID=21203500
|Trait=None
|Title=Genomics Meets Glycomics-The First GWAS Study of Human N-Glycome Identifies HNF1± as a Master Regulator of Plasma Protein Fucosylation
|RiskAllele=G
|Pval=4E-8
|OR=0.1700
|ORtxt=[0.11-0.23] unit increase
|OA=1
}}

{{PMID|18439548|OA=1
}} Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

{{PMID|19672314|OA=1
}} Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs735396
|overall_frequency_n=3123
|overall_frequency_d=10758
|overall_frequency=0.290296
|n_genomes=26
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}