{{Rsnum
|rsid=7354779
|Gene=DNMT3L
|Chromosome=21
|position=44250887
|Orientation=plus
|GMAF=0.1804
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=DNMT3L
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 5.3 | 35.4 | 59.3
| HCB | 0.0 | 13.1 | 86.9
| JPT | 0.0 | 5.3 | 94.7
| YRI | 5.4 | 33.3 | 61.2
| ASW | 5.3 | 38.6 | 56.1
| CHB | 0.0 | 13.1 | 86.9
| CHD | 0.9 | 9.2 | 89.9
| GIH | 1.0 | 20.8 | 78.2
| LWK | 6.4 | 32.7 | 60.9
| MEX | 0.0 | 20.7 | 79.3
| MKK | 3.8 | 29.5 | 66.7
| TSI | 5.9 | 32.4 | 61.8
| HapMapRevision=28
}}{{PMID Auto
|PMID=20593030
|Title=Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking
|OA=1
}}

{{PMID Auto
|PMID=22116073
|Title=Association between single-nucleotide polymorphisms of DNMT3L and infertility with azoospermia in Chinese men
}}

{{PMID Auto
|PMID=22401780
|Title=Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis.
}}

{{GET Evidence
|gene=DNMT3L
|aa_change=Arg278Gly
|aa_change_short=R278G
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7354779
|overall_frequency_n=2682
|overall_frequency_d=10758
|overall_frequency=0.249303
|n_genomes=20
|n_genomes_annotated=0
|n_haplomes=23
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.955
|nblosum100=6
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23922667
|Title=DNA methyltransferase candidate polymorphisms, imprinting methylation, and birth outcome
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}