{{Rsnum
|rsid=737622
|Gene=TTC28
|Chromosome=22
|position=28481727
|Orientation=minus
|GMAF=0.4596
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TTC28
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 29.2 | 49.2 | 21.5
| HCB | 11.1 | 46.7 | 42.2
| JPT | 18.2 | 54.5 | 27.3
| YRI | 30.2 | 44.4 | 25.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 11.1 | 46.7 | 42.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs737622
|Name_s=PICK1:-332 C/G
|Gene_s=-
|Feature=
|Evidence=PubMed ID:17606664
|Annotation=This variant is in the promoter region of PICK1 and in vitro assay showed it significantly altered transcriptional activity.
|Drugs=methamphetamine
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA162263543
}}

{{PMID|17606663}} Identification of functional polymorphisms in the promoter region of the human PICK1 gene and their association with methamphetamine psychosis.

{{PMID|18840782|OA=1
}} Genome-wide linkage and admixture mapping of type 2 diabetes in African American families from the American Diabetes Association GENNID (Genetics of NIDDM) Study Cohort.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs737622
|overall_frequency_n=61
|overall_frequency_d=128
|overall_frequency=0.476562
|n_genomes=41
|n_genomes_annotated=0
|n_haplomes=49
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}