{{Rsnum
|rsid=737866
|Gene=COMT
|Chromosome=22
|position=19942586
|Orientation=minus
|GMAF=0.2392
|Gene_s=COMT,TXNRD2
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 44.2 | 46.0 | 9.7
| HCB | 47.8 | 45.6 | 6.6
| JPT | 45.1 | 46.0 | 8.8
| YRI | 81.6 | 17.0 | 1.4
| ASW | 75.4 | 22.8 | 1.8
| CHB | 47.8 | 45.6 | 6.6
| CHD | 54.1 | 36.7 | 9.2
| GIH | 58.4 | 36.6 | 5.0
| LWK | 75.5 | 20.9 | 3.6
| MEX | 69.0 | 25.9 | 5.2
| MKK | 62.2 | 33.3 | 4.5
| TSI | 51.0 | 40.2 | 8.8
| HapMapRevision=28
}}{{PMID Auto
|PMID=21857968
|Title=Role of novelty seeking personality traits as mediator of the association between COMT and onset age of drug use in Chinese heroin dependent patients
|OA=1
}}

{{PMID Auto
|PMID=18937309
|Title=Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study.
|OA=1
}}

{{PMID Auto
|PMID=19094200
|Title=Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain.
|OA=1
}}

{{PMID Auto
|PMID=21656904
|Title=Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.
|OA=1
}}

{{PMID Auto
|PMID=23155402
|Title=Pathways to Age of Onset of Heroin Use: A Structural Model Approach Exploring the Relationship of the COMT Gene, Impulsivity and Childhood Trauma
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}