{{Rsnum
|rsid=7385804
|Gene=TFR2
|Chromosome=7
|position=100638347
|Orientation=plus
|GMAF=0.3131
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=TFR2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 39.7 | 44.8 | 15.5
| HCB | 56.8 | 37.8 | 5.4
| JPT | 79.1 | 20.9 | 0.0
| YRI | 41.5 | 45.3 | 13.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 56.8 | 37.8 | 5.4
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19820697
|Trait=Hematological parameters
|Title=A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
|RiskAllele=C
|Pval=5E-10
|OR=0.01
|ORtxt=[0.004-0.008] 10^12/l increase
|OA=1
}}

{{PMID Auto GWAS
|PMID=19862010
|Trait=Hematocrit
|Title=Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
|RiskAllele=C
|Pval=4E-10
|OR=0.15
|ORtxt=[0.10-0.20] % decrease
|OA=1
}}

{{PMID Auto GWAS
|PMID=21208937
|Trait=None
|Title=Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels
|RiskAllele=A
|Pval=7E-8
|OR=3.2300
|ORtxt=[2.05-4.41] ug/dl increase
|OA=1
}}

{{PMID|22323359}} TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7385804
|overall_frequency_n=83
|overall_frequency_d=126
|overall_frequency=0.65873
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=71
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23751596
|Title=Association between genetic variations in TFR2 gene and coronary heart disease in Chinese: a case-control study
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}