{{Rsnum
|rsid=740603
|Gene=COMT
|Chromosome=22
|position=19957654
|Orientation=plus
|GMAF=0.4738
|Gene_s=COMT
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 21.5 | 52.3 | 26.2
| HCB | 31.1 | 48.9 | 20.0
| JPT | 22.5 | 52.5 | 25.0
| YRI | 38.1 | 42.9 | 19.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 31.1 | 48.9 | 20.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=23269216
|Title=Association between the COMT gene and rumination in a Hungarian sample
}}

{{PMID Auto
|PMID=16395295
|Title=Significant association of catechol-O-methyltransferase (COMT) haplotypes with nicotine dependence in male and female smokers of two ethnic populations.
}}

{{PMID Auto
|PMID=16848906
|Title=Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans.
|OA=1
}}

{{PMID Auto
|PMID=18436194
|Title=Catechol-O-methyltransferase contributes to genetic susceptibility shared among anxiety spectrum phenotypes.
|OA=1
}}

{{PMID Auto
|PMID=18574484
|Title=The complex global pattern of genetic variation and linkage disequilibrium at catechol-O-methyltransferase.
|OA=1
}}

{{PMID Auto
|PMID=18937309
|Title=Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study.
|OA=1
}}

{{PMID Auto
|PMID=19094200
|Title=Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain.
|OA=1
}}

{{PMID Auto
|PMID=19673036
|Title=Association of tagging single nucleotide polymorphisms on 8 candidate genes in dopaminergic pathway with schizophrenia in Croatian population.
|OA=1
}}

{{PMID Auto
|PMID=19693267
|Title=Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene.
|OA=1
}}

{{PMID Auto
|PMID=19772600
|Title=A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data.
|OA=1
}}

{{PMID Auto
|PMID=21656904
|Title=Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations.
|OA=1
}}

{{PMID Auto
|PMID=22354729
|Title=Association of catechol-O-methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population.
}}

{{PMID Auto
|PMID=23008195
|Title=Genetic variants in the catechol-o-methyltransferase gene are associated with impulsivity and executive function: relevance for major depression.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}