{{Rsnum
|rsid=74315457
|Chromosome=22
|Orientation=minus
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene=ARSA
|position=50626976
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=ARSA
}}{{omim
|id=607574
|rsnum=74315457
|variant=0008
}}{{ClinVar
|rsid=74315457
|Reversed=1
|FwdREF=T
|FwdALT=G
|REF=A
|ALT=C
|RSPOS=51065404
|CHROM=22
|dbSNPBuildID=131
|SSR=0
|SAO=1
|VP=0x050368000000000002110100
|GENEINFO=ARSA:410
|GENE_NAME=ARSA
|GENE_ID=410
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000022.10:g.51065404A>C
|CLNSRC=GeneReviews; OMIM Allelic Variant
|CLNORIGIN=0
|CLNSRCID=NBK1130; 607574.0008; 607574.0041
|CLNSIG=5
|CLNCUI=C0751276; C0751279; C0023522
|CLNDBN=Metachromatic leukodystrophy, juvenile type; Metachromatic leukodystrophy, adult type; Metachromatic leukodystrophy
|Disease=Metachromatic leukodystrophy; Metachromatic leukodystrophy; Metachromatic leukodystrophy
|CLNACC=RCV000003202.1; RCV000003203.1; RCV000020320.1
|Tags=RV;PM;PMC;S3D;SLO;OTHERKG;LSD;OM
|CLNDSDB=MedGen:SNOMED_CT; GeneReviews:MedGen:OMIM:Orphanet:SNOMED_CT
|CLNDSDBID=C0751276:44359008; C0751279:24326000; NBK1130:C0023522:250100:512:396338004
}}{{PMID Auto
|PMID=1684088
|Title=Two new arylsulfatase A (ARSA) mutations in a juvenile metachromatic leukodystrophy (MLD) patient.
|OA=1
}}

{{PMID Auto
|PMID=12081727
|Title=High prevalence of I179S mutation in patients with late-onset metachromatic leukodystrophy.
}}