{{Rsnum
|rsid=74799832
|Chromosome=10
|Orientation=plus
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene=RET
|position=43121968
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=RET
}}{{omim
|id=164761
|rsnum=74799832
|variant=0013
}}{{ClinVar
|rsid=74799832
|Reversed=0
|FwdREF=T
|FwdALT=C
|REF=T
|ALT=C
|RSPOS=43617416
|CHROM=10
|dbSNPBuildID=131
|SSR=0
|SAO=3
|VP=0x050268000000000002110120
|GENEINFO=RET:5979
|GENE_NAME=RET
|GENE_ID=5979
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000010.10:g.43617416T>C
|CLNSRC=Emory University; GTR; OMIM Allelic Variant
|CLNORIGIN=0
|CLNSRCID=5658; GTR000005812; 164761.0013
|CLNSIG=255
|CLNCUI=C0025269; C1619700; C0025269
|CLNDBN=Multiple endocrine neoplasia, type 2b; Thyroid carcinoma, sporadic medullary; Pheochromocytoma, somatic; Renal adysplasia; not provided
|Disease=Multiple endocrine neoplasia; Thyroid carcinoma; Pheochromocytoma; Renal adysplasia; not provided
|CLNACC=RCV000014941.24; RCV000014942.20; RCV000014943.1; RCV000014944.24; RCV000082054.1
|Tags=PM;PMC;S3D;OTHERKG;LSD;OM
|CLNDSDB=GeneReviews:MedGen:OMIM:Orphanet:SNOMED_CT:SNOMED_CT; MedGen:OMIM:Orphanet
|CLNDSDBID=NBK1257:C0025269:162300:653:6153000:61530001; C1619700:191830:1848
}}{{PMID|88}} The oxygen affinity of haemoglobin Tak, a variant with an elongated beta chain.

{{PMID|3078962}} Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains.

{{PMID|7536460}} Mutation of the RET protooncogene in sporadic medullary thyroid carcinoma.

{{PMID|7824936}} Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B.

{{PMID|7906417|OA=1
}} Single missense mutation in the tyrosine kinase catalytic domain of the RET protooncogene is associated with multiple endocrine neoplasia type 2B.

{{PMID|7906866}} A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma.

{{PMID|7911697}} Point mutation within the tyrosine kinase domain of the RET proto-oncogene in multiple endocrine neoplasia type 2B and related sporadic tumours.