{{Rsnum
|rsid=7538490
|Gene=NOS1AP
|Chromosome=1
|position=162121540
|Orientation=plus
|GMAF=0.3343
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=NOS1AP
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 48.4 | 45.3 | 6.2
| HCB | 24.4 | 48.9 | 26.7
| JPT | 27.3 | 34.1 | 38.6
| YRI | 50.8 | 38.1 | 11.1
| ASW | 0.0 | 0.0 | 0.0
| CHB | 24.4 | 48.9 | 26.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

The T-allele of [[NOS1AP]] [[rs3020781]] was previously reported to be strongly associated with [[type-2 diabetes]] in various European-descent populations comprising a total of 2,198 individuals with a combined odds ratio (OR) of 1.53 [1.28-1.81].

However, in a combined study sample comprising a total of 16,801 and 16,913 individuals from Denmark, no significant association was found to diabetes or obesity.{{PMID|19111066|OA=1
}}

{{PMID Auto
|PMID=19389826
|Title=Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}