{{Rsnum
|rsid=7539542
|Gene=ADIPOR1
|Chromosome=1
|position=202940846
|Orientation=plus
|GMAF=0.4986
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=ADIPOR1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 50.0 | 42.2 | 7.8
| HCB | 11.9 | 38.1 | 50.0
| JPT | 2.3 | 32.6 | 65.1
| YRI | 0.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 11.9 | 38.1 | 50.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}A study of 733 [[breast cancer]] cases for 10 SNPs concluded that a [[rs7539542]] genotype was associated with decreased risk (odds ratio 0.51, CI: 0.28-0.92).{{PMID|18451143|OA=1
}}

After categorizing individuals by adiponectin signaling status, this study found that compared with high signalers, intermediate signalers had a 4.16-fold increase in breast cancer risk (CI: 0.49-35.19), and low signalers had a 6.56x higher [[breast cancer]] risk (CI: 0.78-54.89, p(trend) = 0.001).{{PMID|18451143|OA=1
}}

Adiponectin signaling status was assigned as follows:

rs1501299(G,G) + rs2241766(T,T) = low signaler<br>
rs1501299(G,T) + rs2241766(T,T) = low signaler<br>
rs1501299(G,G) + rs2241766(G,T) = low signaler<br>
rs1501299(T,T) + rs2241766(T,T) = intermediate signaler<br>
rs1501299(G,T) + rs2241766(G,T) = intermediate signaler<br>
rs1501299(G,G) + rs2241766(G,G) = intermediate signaler<br>
rs1501299(G,T) + rs2241766(G,G) = high signaler<br>
rs1501299(T,T) + rs2241766(G,G) = high signaler<br>
rs1501299(T,T) + rs2241766(G,T) = high signaler<br>

{{PMID Auto
|PMID=21397927
|Title=Polymorphisms of ADIPOQ and ADIPOR1 and prostate cancer risk
|OA=1
}}

{{PMID Auto
|PMID=16724230
|Title=Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study.
}}

{{PMID Auto
|PMID=16955209
|Title=Association between variants in the genes for adiponectin and its receptors with insulin resistance syndrome (IRS)-related phenotypes in Mexican Americans.
}}

{{PMID Auto
|PMID=17216283
|Title=Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.
|OA=1
}}

{{PMID Auto
|PMID=18827209
|Title=Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk.
|OA=1
}}

{{PMID Auto
|PMID=19037660
|Title=The association of SNPs in ADIPOQ, ADIPOR1, and ADIPOR2 with insulin sensitivity in a cohort of adolescents and their parents.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}