{{Rsnum
|rsid=754203
|Gene=CYP46A1
|Chromosome=14
|position=99691630
|Orientation=minus
|GMAF=0.2897
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CYP46A1
}}{{PMID Auto
|PMID=19553612
|Title=Primary Open Angle Glaucoma: Association with Cholesterol 24S-Hydroxylase (CYP46A1) Gene Polymorphism and Plasma 24-Hydroxycholesterol Levels
}}

{{PMID Auto
|PMID=19705089
|Title=Cyp46 Polymorphisms in Alzheimer's Disease: A Review
}}

{{PMID Auto
|PMID=22528464
|Title=An Intronic CYP46A1 Polymorphism Is Associated with Alzheimer Disease in a Chinese Han Population
}}

{{PMID|15034781}} Variants of CYP46A1 may interact with age and APOE to influence CSF Abeta42 levels in Alzheimer's disease.

{{PMID|15936520}} CYP46: a risk factor for Alzheimer's disease or a coincidence?

{{PMID|16340204}} Polymorphism in the cholesterol 24S-hydroxylase gene (CYP46A1) associated with the APOEpsilon3 allele increases the risk of Alzheimer's disease and of mild cognitive impairment progressing to Alzheimer's disease.

{{PMID|16960449}} Intron 2 (T/C) CYP46 polymorphism is associated with Alzheimer's disease in Chinese patients.

{{PMID|18280754|OA=1
}} Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions.

{{PMID|19363267}} Earlier onset of Alzheimer's disease: risk polymorphisms within PRNP, PRND, CYP46, and APOE genes.

{{PMID|20682755|OA=1
}} A pilot study of gene/gene and gene/environment interactions in Alzheimer disease.

{{PMID|21386929|OA=1
}} Role of cholesterol 24S-hydroxylase gene polymorphism (rs754203) in primary open angle glaucoma.

{{PMID|21531213}} 24S-hydroxycholesterol and cholesterol-24S-hydroxylase (CYP46A1) in the retina: from cholesterol homeostasis to pathophysiology of glaucoma.

{{PMID Auto
|PMID=22977134
|Title=Single nucleotide polymorphism in the cholesterol-24S-hydroxylase (CYP46A1) gene and its association with CFH and LOC387715 gene polymorphisms in AMD
}}

{{PMID Auto
|PMID=23167762
|Title=Association of CYP46 gene polymorphism with sporadic Alzheimer's disease in Chinese Han populations: A meta-analysis
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}