{{Rsnum
|rsid=757110
|Gene=ABCC8
|Chromosome=11
|position=17396930
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=T
|GMAF=0.2856
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=ABCC8
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 12.6 | 52.3 | 35.1
| HCB | 16.8 | 44.5 | 38.7
| JPT | 14.2 | 46.9 | 38.9
| YRI | 0.0 | 0.0 | 100.0
| ASW | 3.5 | 22.8 | 73.7
| CHB | 16.8 | 44.5 | 38.7
| CHD | 11.0 | 52.3 | 36.7
| GIH | 16.8 | 49.5 | 33.7
| LWK | 0.0 | 0.9 | 99.1
| MEX | 17.2 | 50.0 | 32.8
| MKK | 0.0 | 3.2 | 96.8
| TSI | 8.8 | 44.1 | 47.1
| HapMapRevision=28
}}

{{Venter SNP
|rsid=757110
|allele=A
|frequency=0.6
|uid=1103649619631
|type=homozygous_SNP
|hugo=ABCC8
|ensembl gene=ENSG00000006071
|ensembl transcript=ENST00000302539
|sift=TOLERATED
|disease=Defects in ABCC8 may contribute to non-insulin-dependent diabetes mellitus (NIDDM), also known as type II diabetes mellitus, in Northern European Caucasians.
}}

{{ neighbor
| rsid = 28936370
| distance = 50
}}

{{PMID Auto
|PMID=16642433
|Title=Polymorphism in maternal LRP8 gene is associated with fetal growth.
|OA=1
}}

{{PMID Auto
|PMID=17903298
|Title=Genome-wide association with diabetes-related traits in the Framingham Heart Study.
|OA=1
}}

{{PMID Auto
|PMID=18599530
|Title=Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.
|OA=1
}}

{{PMID Auto
|PMID=19641380
|Title=Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans.
|OA=1
}}

{{GET Evidence
|gene=ABCC8
|aa_change=Ala1369Ser
|aa_change_short=A1369S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs757110
|overall_frequency_n=7947
|overall_frequency_d=10758
|overall_frequency=0.738706
|n_genomes=45
|n_genomes_annotated=0
|n_haplomes=77
|n_articles=0
|n_articles_annotated=0
|qualityscore_in_silico=3
|qualitycomment_in_silico=Y
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=-1
|autoscore=3
|n_web_uneval=10
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}