{{Rsnum
|rsid=7590268
|Gene=THADA
|Chromosome=2
|position=43312986
|Orientation=plus
|GMAF=0.1667
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=THADA
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 3.5 | 37.2 | 59.3
| HCB | 0.0 | 10.4 | 89.6
| JPT | 0.0 | 5.4 | 94.6
| YRI | 2.7 | 31.3 | 66.0
| ASW | 7.0 | 22.8 | 70.2
| CHB | 0.0 | 10.4 | 89.6
| CHD | 0.0 | 7.4 | 92.6
| GIH | 5.0 | 29.7 | 65.3
| LWK | 4.6 | 35.8 | 59.6
| MEX | 1.7 | 19.0 | 79.3
| MKK | 3.2 | 28.4 | 68.4
| TSI | 3.9 | 42.2 | 53.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20023658
|Trait=Nonsyndromic cleft lip with or without cleft palate
|Title=Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate
|RiskAllele=G
|Pval=9E-8
|OR=1.42
|ORtxt=[1.26-1.59]
}}
Associated with European Facial [[Appearance]] {{doi|10.1371/journal.pgen.1002932}}
*[[rs7590268]]
*[[rs16903544]]
*[[rs987525]]
*[[rs9574565]]
*[[rs227731]]
*[[rs642961]] 
*[[rs1258763]]
 

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7590268
|overall_frequency_n=30
|overall_frequency_d=128
|overall_frequency=0.234375
|n_genomes=21
|n_genomes_annotated=0
|n_haplomes=25
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23536526
|Title=Association and cumulative effects of GWAS-identified genetic variants for nonsyndromic orofacial clefts in a Chinese population
}}

{{PMID Auto GWAS
  |PMID=22863734
  |Trait=Orofacial clefts
  |Title=Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.
  |RiskAllele=G
  |Pval=1E-8
  |OR=1.42
  |ORtxt=[1.225-1.636]
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}