{{Rsnum
|rsid=7595412
|Gene=PLCL1
|Chromosome=2
|position=198097519
|Orientation=plus
|GMAF=0.06198
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PLCL1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 73.5 | 26.5 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 93.9 | 6.1 | 0.0
| ASW | 84.2 | 15.8 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 88.1 | 11.9 | 0.0
| LWK | 86.4 | 10.9 | 2.7
| MEX | 82.8 | 17.2 | 0.0
| MKK | 95.5 | 4.5 | 0.0
| TSI | 93.1 | 5.9 | 1.0
| HapMapRevision=28
}}{{GWAS Summary
|SNP=rs7595412
|PubMedID=18776929
|Condition=Hip bone size
|Gene=PLCL1
|Risk Allele=A
|pValue=2.00E-006
|OR=5
|95CI=NR) cm2 increase in hip bone size on wome
|OA=1
}}

{{PharmGKB
|RSID=rs7595412
|Name_s=
|Gene_s=PLCL1
|Feature=
|Evidence=PubMed ID:18776929; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study (Initial Sample Size: 501 women, 499 men; Replication Sample Size: 1,216 women; Risk Allele: rs7595412-A). This variant is associated with Hip bone size.
|Drugs=
|Drug Classes=
|Diseases=Bone Diseases; Bone Diseases, Metabolic; Fractures, Bone
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356550
}}
{{PMID Auto
|PMID=20030815
|Title=PLCL1 rs7595412 variation is not associated with hip bone size variation in postmenopausal Danish women
|OA=1
}}

{{PharmGKB
|RSID=rs7595412
|Name_s=
|Gene_s=PLCL1
|Feature=
|Evidence=PubMed ID:18776929
|Annotation=This variant is associated with hip bone size in a genome-wide association study (GWAS) consisting of 1,000 homogeneous unrelated Caucasian subjects.
|Drugs=
|Drug Classes=
|Diseases=Fractures, Bone; Hip Fractures; Hip Injuries; Osteoporosis
|Curation Level=Curated
|PharmGKB Accession ID=PA162316701
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7595412
|overall_frequency_n=121
|overall_frequency_d=128
|overall_frequency=0.945312
|n_genomes=55
|n_genomes_annotated=0
|n_haplomes=104
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}