{{Rsnum
|rsid=760761
|Gene=DTNBP1
|Chromosome=6
|position=15650901
|Orientation=plus
|GMAF=0.2218
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=DTNBP1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 62.5 | 28.1 | 9.4
| HCB | 86.7 | 13.3 | 0.0
| JPT | 84.4 | 13.3 | 2.2
| YRI | 38.1 | 52.4 | 9.5
| ASW | 0.0 | 0.0 | 0.0
| CHB | 86.7 | 13.3 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

[http://genes2brains2mentalhealth.wordpress.com/2007/12/21/i-carry-genetic-risk-for-mental-illness/ g2b2mh blog] In a population of healthy individuals, those that carry common variants (such as [[rs760761]], [[rs1018381]], [[rs2619522]]) located in the dysbindin (DTNBP1) gene, a risk factor for [[schizophrenia]], show minor cognitive impairments such as decreased attentional capacity, worse performance on [[memory]] tasks, and alterations in schizotypal beliefs and experiences.

{{PMID|19800201|OA=1
}} The association between several SNPs in the [[DTNBP1]] gene, most especially [[rs760761]], and [[schizophrenia]] was confirmed in a new sample of 1021 cases and 626 controls from Ireland.

{{PMID Auto
|PMID=18804346
|Title=Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia
|OA=1
}}

{{PMID Auto
|PMID=19252939
|Title=Dysbindin gene (DTNBP1) and schizophrenia in Korean population
}}

{{PMID|12098102|OA=1
}} Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.

{{PMID|12474144|OA=1
}} Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families.

{{PMID|14618545|OA=1
}} The DTNBP1 (dysbindin) gene contributes to schizophrenia, depending on family history of the disease.

{{PMID|15290652|OA=1
}} A powerful strategy to account for multiple testing in the context of haplotype analysis.

{{PMID|15362017|OA=1
}} Association of the DTNBP1 locus with schizophrenia in a U.S. population.

{{PMID|17033966|OA=1
}} Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.

{{PMID|17074466|OA=1
}} DTNBP1 genotype influences cognitive decline in schizophrenia.

{{PMID|17192893}} Effect of 5-haplotype of dysbindin gene (DTNBP1) polymorphisms for the susceptibility to bipolar I disorder.

{{PMID|17264804}} Dysbindin associated with selective serotonin reuptake inhibitor antidepressant efficacy.

{{PMID|17336946}} Impact of schizophrenia candidate genes on schizotypy and cognitive endophenotypes at the population level.

{{PMID|17445278|OA=1
}} Association between the DTNBP1 gene and intelligence: a case-control study in young patients with schizophrenia and related disorders and unaffected siblings.

{{PMID|17888175|OA=1
}} Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia.

{{PMID|17964051}} Is there protective haplotype of dysbindin gene (DTNBP1) 3 polymorphisms for major depressive disorder.

{{PMID|18663367|OA=1
}} The dystrobrevin-binding protein 1 gene: features and networks.

{{PMID|18715757|OA=1
}} Genetic associations with schizophrenia: meta-analyses of 12 candidate genes.

{{PMID|18797396}} Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression.

{{PMID|19065121}} Dysbindin gene (DTNBP1) in major depression: association with clinical response to selective serotonin reuptake inhibitors.

{{PMID|19089808}} Association of the dystrobrevin binding protein 1 gene (DTNBP1) in a bipolar case-control study (BACCS).

{{PMID|19197363|OA=1
}} A genome-wide investigation of SNPs and CNVs in schizophrenia.

{{PMID|19369910|OA=1
}} The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation.

{{PMID|20046352|OA=1
}} Effect of the dysbindin gene on antimanic agents in patients with bipolar I disorder.

{{PMID|20822372}} Dysbindin gene (DTNBP1) in major depressive disorder (MDD) patients: lack of association with clinical phenotypes.

{{PMID Auto
|PMID=22911901
|Title=Association of genetic variations in DTNBP1 with cognitive function in schizophrenia patients and healthy subjects.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}