{{Rsnum
|rsid=763110
|Gene=FASLG
|Chromosome=1
|position=172658358
|Orientation=plus
|GMAF=0.4311
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=FASLG
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 36.0 | 48.6 | 15.3
| HCB | 56.6 | 40.4 | 2.9
| JPT | 56.8 | 36.9 | 6.3
| YRI | 0.7 | 17.0 | 82.3
| ASW | 5.3 | 45.6 | 49.1
| CHB | 56.6 | 40.4 | 2.9
| CHD | 50.5 | 43.1 | 6.4
| GIH | 16.0 | 46.0 | 38.0
| LWK | 1.8 | 18.2 | 80.0
| MEX | 41.1 | 55.4 | 3.6
| MKK | 5.1 | 43.6 | 51.3
| TSI | 35.3 | 51.0 | 13.7
| HapMapRevision=28
}}
[[rs763110]], also known as -844C>T, is a SNP in the FAS ligand [[FASLG]] gene.

A meta-analysis of 19 published studies, including 11,105 cancer cases and 11,372 controls, concluded that the [[rs763110]](C;T) and (T;T) genotypes were associated with a significantly reduced (about 0.80x) cancer risk of all cancer types.{{PMID|19337311|OA=1
}}

{{PMID Auto
|PMID=19240174
|Title=Polymorphisms in the FAS and FASL genes and survival of early stage non-small cell lung cancer.
}}

{{PMID Auto
|PMID=21807637
|Title=A Polymorphic -844T/C in FasL Promoter Predicts Survival and Relapse in Non-Small Cell Lung Cancer
}}

{{PMID Auto
|PMID=22732091
|Title=FASL -844 T/C polymorphism: A biomarker of good prognosis of breast cancer in the Tunisian population
}}

{{ClinVar
|rsid=763110
|Reversed=0
|FwdREF=C
|FwdALT=T
|REF=C
|ALT=T
|RSPOS=172627498
|CHROM=1
|GMAF=0.4313
|dbSNPBuildID=86
|SSR=0
|SAO=1
|VP=0x05016800000017051f110100
|GENEINFO=FASLG:356
|GENE_NAME=FASLG
|GENE_ID=356
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.10:g.172627498C>T
|CLNORIGIN=0
|CLNSIG=255
|Tags=PM;PMC;SLO;VLD;G5A;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.5689; 0.4311
|CLNACC=RCV000017960.1; RCV000020368.2
|CLNDBN=Lung cancer, susceptibility to; Lung cancer
|CLNDSDB=GeneReviews:MedGen:OMIM:SNOMED_CT
|CLNDSDBID=NBK1108:C0684249:211980:187875007
|CLNSRC=GeneReviews; OMIM Allelic Variant
|CLNSRCID=NBK1108; 134638.0002
|COMMON=1
|Disease=Lung cancer; Lung cancer
}}

{{PMID Auto
|PMID=18757527
|Title=Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer.
|OA=1
}}

{{PMID Auto
|PMID=18759263
|Title=Features associated with, and the impact of, hemolytic anemia in patients with systemic lupus erythematosus: LX, results from a multiethnic cohort.
|OA=1
}}

{{PMID Auto
|PMID=18805939
|Title=Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
|OA=1
}}

{{PMID Auto
|PMID=18854777
|Title=Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.
|OA=1
}}

{{PMID Auto
|PMID=19941645
|Title=Fas and FasL gene polymorphisms are not associated with cervical cancer but differ among Black and Mixed-ancestry South Africans.
|OA=1
}}

{{PMID Auto
|PMID=20438363
|Title=Fas and FasL polymorphisms are not associated with acute myeloid leukemia risk in Koreans.
}}

{{PMID Auto
|PMID=20959405
|Title=The IFNG (IFN-gamma) genotype predicts cytogenetic and molecular response to imatinib therapy in chronic myeloid leukemia.
}}

{{PMID Auto
|PMID=15937082
|Title=Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer.
|OA=1
}}

{{PMID Auto
|PMID=23141929
|Title=A Controlled Case Study of the Relationship Between Environmental Risk Factors and Apoptotic Gene Polymorphism and Lumbar Disc Herniation
}}

{{PMID Auto
|PMID=23392773
|Title=Apoptosis-related Fas and FasL gene polymorphisms' associations with knee osteoarthritis
}}

{{PMID Auto
|PMID=24086353
|Title=FASL rs763110 Polymorphism Contributes to Cancer Risk: An Updated Meta-Analysis Involving 43,295 Subjects
|OA=1
}}

{{PMID Auto
|PMID=24424626
|Title=Association of genetic variants in apoptosis genes FAS and FASL with radiation-induced late toxicity after prostate cancer radiotherapy
}}

{{PMID Auto
|PMID=24587306
|Title=Death Receptor (DR4) Haplotypes Are Associated with Increased Susceptibility of Gallbladder Carcinoma in North Indian Population
|OA=1
}}

{{PMID Auto
|PMID=23749041
|Title=Relation of the Fas and FasL gene polymorphisms with susceptibility to and severity of rheumatoid arthritis.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}