{{Rsnum
|rsid=763317
|Gene=EGFR
|Chromosome=7
|position=55027504
|Orientation=plus
|GMAF=0.3485
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=EGFR
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 19.5 | 44.2 | 36.3
| HCB | 4.4 | 32.8 | 62.8
| JPT | 2.7 | 32.7 | 64.6
| YRI | 12.2 | 44.9 | 42.9
| ASW | 15.8 | 40.4 | 43.9
| CHB | 4.4 | 32.8 | 62.8
| CHD | 5.5 | 42.2 | 52.3
| GIH | 19.8 | 41.6 | 38.6
| LWK | 5.5 | 45.5 | 49.1
| MEX | 8.6 | 44.8 | 46.6
| MKK | 9.0 | 54.5 | 36.5
| TSI | 31.4 | 49.0 | 19.6
| HapMapRevision=28
}}[[rs763317]], also known as 8227A>G, is a SNP located in the first intron of the epidermal growth factor receptor [[EGFR]] gene.

In a study of 730 Taiwanese patients with [[lung cancer]] and matched controls, never-smoking females having at least one [[rs763317]](A) allele were at increased risk (p = 0.009) for adenocarcinomas; the adjusted odds ratio for the (A;G) genotype was 1.23, CI: 0.87-1.75, and for the (A;A) genotype, the odds ratio was 3.52, CI: 1.32-9.37.{{PMID|19026460}}

{{PMID Auto
|PMID=20068085
|Title=Analysis of Genetic Variants in Never-Smokers with Lung Cancer Facilitated by an Internet-Based Blood Collection Protocol: A Preliminary Report
|OA=1
}}

{{PMID Auto
|PMID=19190167
|Title=A two-stage case-control study of EGFR polymorphisms and breast cancer risk.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}