{{Rsnum
|rsid=763780
|Gene=IL17F
|Chromosome=6
|position=52236941
|Orientation=plus
|GMAF=0.07989
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=IL17F
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 9.7 | 90.3
| HCB | 2.9 | 24.8 | 72.3
| JPT | 2.7 | 20.4 | 77.0
| YRI | 0.0 | 14.3 | 85.7
| ASW | 0.0 | 14.0 | 86.0
| CHB | 2.9 | 24.8 | 72.3
| CHD | 2.8 | 22.9 | 74.3
| GIH | 1.0 | 12.9 | 86.1
| LWK | 0.0 | 5.5 | 94.5
| MEX | 0.0 | 17.2 | 82.8
| MKK | 0.0 | 9.0 | 91.0
| TSI | 0.0 | 9.8 | 90.2
| HapMapRevision=28
}}

No association seen in the following report:
{{PMID Auto
|PMID=19414056
|Title=Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis
}}

{{PMID Auto
|PMID=19724898
|Title=Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa
}}

{{PMID Auto
|PMID=21615796
|Title=Interleukin-17F gene polymorphism in patients with chronic immune thrombocytopenia
}}

{{PMID Auto
|PMID=22118860
|Title=Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese - A case control study
}}

{{PMID Auto
|PMID=22142827
|Title=A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303
|OA=1
}}

{{PMID Auto
|PMID=22312940
|Title=Interleukin 17A and F and asthma in Saudi Arabia: gene polymorphisms and protein levels.
}}

{{PMID Auto
|PMID=16630936
|Title=IL-17F sequence variant (His161Arg) is associated with protection against asthma and antagonizes wild-type IL-17F activity.
}}

{{PMID Auto
|PMID=17828618
|Title=The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis.
}}

{{PMID Auto
|PMID=18774769
|Title=Lower frequency of IL-17F sequence variant (His161Arg) in chronic fatigue syndrome patients.
}}

{{PMID Auto
|PMID=20618772
|Title=Association between IL-17F gene polymorphisms and susceptibility to and severity of rheumatoid arthritis (RA).
}}

{{PMID Auto
|PMID=20620187
|Title=Interleukin-17 gene polymorphism is associated with Vogt-Koyanagi-Harada syndrome but not with Behcet's disease in a Chinese Han population.
}}

{{PMID Auto
|PMID=22692973
|Title=Interleukin-17 gene polymorphisms are associated with bladder cancer in a Chinese Han population.
}}

{{PMID Auto
|PMID=23049595
|Title=Association between IL17 Polymorphisms and Risk of Cervical Cancer in Chinese Women
|OA=1
}}

{{GET Evidence
|gene=IL17F
|aa_change=His161Arg
|aa_change_short=H161R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs763780
|overall_frequency_n=678
|overall_frequency_d=10758
|overall_frequency=0.0630229
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.457
|nblosum100=1
|autoscore=1
|n_web_uneval=10
}}

{{PMID Auto
|PMID=23111159
|Title=Genetic association between IL-17F gene polymorphisms and the pathogenesis of Graves' Disease in the Han Chinese population
}}

{{PMID Auto
|PMID=23376081
|Title=Analysis of IL-17 gene polymorphisms in Chinese patients with dilated cardiomyopathy
}}

{{PMID Auto
|PMID=23519962
|Title=Association of Interleukin-17F Gene Polymorphism with Enterovirus 71 Encephalitis in Patients with Hand, Foot, and Mouth Disease
}}

{{PMID Auto
|PMID=23652560
|Title=Genetic polymorphisms of interleukin 17A and interleukin 17F and their association with inflammatory bowel disease in a Chinese Han population
}}

{{PMID Auto
|PMID=23137879
|Title=Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis
}}

{{PMID Auto
|PMID=24164796
|Title=Interleukin-17F single-nucleotide polymorphism (7488T&gt;C) and its association with susceptibility to leprosy
}}

{{PMID Auto
|PMID=24315816
|Title=Effect of interleukin-17A and interleukin-17F gene polymorphisms on the risk of gastric cancer in a Chinese population
}}

{{PMID Auto
|PMID=22573572
|Title=Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in autophagy-related genes (GOIA study II).
}}

{{PMID Auto
|PMID=22579472
|Title=The IL6 gene polymorphism -634C>G and IL17F gene polymorphism 7488T>C influence bone mineral density in young and elderly Japanese women.
}}

{{PMID Auto
|PMID=22816799
|Title=Association of interleukin-17A and -17F gene single-nucleotide polymorphisms with autoimmune thyroid diseases.
}}

{{PMID Auto
|PMID=23219503
|Title=The IL-17F sequence variant is associated with susceptibility to tuberculosis.
}}

{{PMID Auto
|PMID=24857622
|Title=IL-17F but not IL-17A gene polymorphism confers risk to multiple sclerosis in a Chinese Han population
}}

{{PMID Auto
|PMID=24935327
|Title=Haplotype Analysis on Chromosome 6p of Tumor Necrosis Factor Alpha, Vascular Endothelial Growth Factor A, and Interleukin-17F Alleles Associated With Corneal Transplant Rejection
}}

{{PMID Auto
|PMID=25012243
|Title=IL-17 gene polymorphism is associated with susceptibility to gastric cancer
}}

{{PMID Auto
|PMID=25227691
|Title=Association of IL-17A and IL-17 F gene polymorphisms with recurrent pregnancy loss in Iranian women
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}