{{Rsnum
|rsid=7702187
|Gene=SEMA5A
|Chromosome=5
|position=9332169
|Orientation=plus
|GMAF=0.32
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;T)
|geno3=(T;T)
|Gene_s=SEMA5A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;T)
| geno3=(T;T)
| CEU | 63.9 | 34.4 | 1.6
| HCB | 44.4 | 46.7 | 8.9
| JPT | 47.7 | 45.5 | 6.8
| YRI | 11.9 | 42.4 | 45.8
| ASW | 0.0 | 0.0 | 0.0
| CHB | 44.4 | 46.7 | 8.9
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}rs7702187 increases susceptibility to Parkinson's disease 1.74 times for carriers of the A allele {{PMID|16252231|OA=1
}}

{{PMID|18950607}} [[rs7702187]] had no association with the risk of developing [[Parkinson's disease]] in a study of 340 Han Chinese patients.

{{ neighbor
| rsid = 6896702
| distance = 433
}}

{{GWAS Summary
|SNP=rs7702187
|PubMedID=16252231
|Condition=Parkinson's disease
|Gene=SEMA5A
|Risk Allele=
|pValue=8.00E-006
|OR=1.74
|95CI=1.36-2.24
|OA=1
}}

{{omim
|desc=PARKINSON DISEASE; PD
|id=168600
|rsnum=7702187
}}

{{PharmGKB
|RSID=rs7702187
|Name_s=
|Gene_s=SEMA5A
|Feature=
|Evidence=PubMed ID:16252231; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: High-resolution whole-genome association study of Parkinson disease (Initial Sample Size: 443 sib pairs; Replication Sample Size: 332 cases, 332 controls). This variant is associated with Parkinson's disease.
|Drugs=
|Drug Classes=
|Diseases=Parkinson Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356546
}}

{{PMID Auto
|PMID=16481103
|Title=Polymorphism in semaphorin 5A (Sema5A) gene is not a marker of Parkinson's disease risk.
}}

{{PMID Auto
|PMID=16685660
|Title=Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease.
|OA=1
}}

{{PMID Auto
|PMID=16685661
|Title=Genomewide association, Parkinson disease, and PARK10.
|OA=1
}}

{{PMID Auto
|PMID=16685662
|Title=No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.
|OA=1
}}

{{PMID Auto
|PMID=16685663
|Title=A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan.
|OA=1
}}

{{PMID Auto
|PMID=19957501
|Title=[Correlation study of semaphorin 5a with risk of Parkinson's disease in a Chinese Han population].
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7702187
|overall_frequency_n=80
|overall_frequency_d=128
|overall_frequency=0.625
|n_genomes=42
|n_genomes_annotated=0
|n_haplomes=66
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}