{{Rsnum
|rsid=7703051
|Chromosome=5
|position=75329662
|Orientation=plus
|GMAF=0.4201
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 16.8 | 46.0 | 37.2
| HCB | 29.2 | 49.6 | 21.2
| JPT | 25.7 | 57.5 | 16.8
| YRI | 7.5 | 47.3 | 45.2
| ASW | 14.0 | 33.3 | 52.6
| CHB | 29.2 | 49.6 | 21.2
| CHD | 32.1 | 46.8 | 21.1
| GIH | 42.6 | 46.5 | 10.9
| LWK | 15.5 | 50.9 | 33.6
| MEX | 14.0 | 33.3 | 52.6
| MKK | 11.5 | 41.0 | 47.4
| TSI | 15.7 | 45.1 | 39.2
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=18802019
|Trait=LDL cholesterol
|Title=Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13
|RiskAllele=A
|Pval=1E-8
|OR=18.00
|ORtxt=[NR] % SD increase
|OA=1
}}

{{PharmGKB
|RSID=rs7703051
|Name_s=
|Gene_s=HMGCR
|Feature=
|Evidence=PubMed ID:18802019; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common SNPs in HMGCR in Micronesians and Whites Associated With LDL-Cholesterol Levels Affect Alternative Splicing of Exon13. (Initial Sample Size: 2,346 Micronesian individuals; Replication Sample Size: 1,464 European white cases, 1,467 European white controls); (Region: 5q13.3; Reported Gene(s): HMGCR; Risk Allele: rs7703051-A); (p-value= 0.00000001).This variant is associated with LDL cholesterol.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740852
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7703051
|overall_frequency_n=51
|overall_frequency_d=128
|overall_frequency=0.398438
|n_genomes=36
|n_genomes_annotated=0
|n_haplomes=45
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}