{{Rsnum
|rsid=7753394
|Chromosome=6
|position=137764111
|Orientation=plus
|GMAF=0.4343
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 24.1 | 55.4 | 20.5
| HCB | 2.2 | 28.5 | 69.3
| JPT | 6.2 | 20.4 | 73.5
| YRI | 34.0 | 46.9 | 19.0
| ASW | 29.8 | 54.4 | 15.8
| CHB | 2.2 | 28.5 | 69.3
| CHD | 4.6 | 37.0 | 58.3
| GIH | 47.5 | 46.5 | 5.9
| LWK | 40.0 | 46.4 | 13.6
| MEX | 39.7 | 41.4 | 19.0
| MKK | 30.8 | 57.7 | 11.5
| TSI | 22.5 | 49.0 | 28.4
| HapMapRevision=28
}}[[rs7753394]] has been reported in a large study to be associated with [[Crohn's disease]].

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.21 (CI 1.04-1.40), and for homozygotes, 1.48 (CI 1.25-1.76). {{PMID|17554300|OA=1
}}

{{PMID Auto
|PMID=18438406
|Title=Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
|OA=1
}}

{{PMID Auto
|PMID=19956648
|Title=Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.
|OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}