{{Rsnum
|rsid=7767084
|Gene=LPA
|Chromosome=6
|position=160541471
|Orientation=plus
|GMAF=0.1575
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LPA
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 3.5 | 24.8 | 71.7
| HCB | 8.8 | 41.6 | 49.6
| JPT | 12.4 | 41.6 | 46.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 5.3 | 94.7
| CHB | 8.8 | 41.6 | 49.6
| CHD | 12.8 | 35.8 | 51.4
| GIH | 2.0 | 47.0 | 51.0
| LWK | 0.0 | 4.5 | 95.5
| MEX | 0.0 | 16.1 | 83.9
| MKK | 0.0 | 18.6 | 81.4
| TSI | 3.9 | 26.5 | 69.6
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs7767084
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19198611; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. (Initial Sample Size: 1,926 cases, 2,938 controls; Replication Sample Size: 7,073 cases, 7,325 controls); (Region: 6q25.3; Reported Gene(s): SLC22A3,LPAL2,LPA; Risk Allele: 4-SNP haplotype-1); (p-value= 0.000000001).This variant is associated with Coronary artery disease.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739974
}}

{{PharmGKB
|RSID=rs7767084
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19198611; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. (Initial Sample Size: 1,926 cases, 2,938 controls; Replication Sample Size: 7,073 cases, 7,325 controls); (Region: 6q25.3; Reported Gene(s): SLC22A3,LPAL2,LPA; Risk Allele: 4-SNP haplotype-2); (p-value= 0.000000000000004).This variant is associated with Coronary artery disease.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739980
}}

{{PMID Auto
|PMID=19956433
|Title=Genetics of coronary artery disease: focus on genome-wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=21305047
|Title=Variation in LPA is associated with Lp(a) levels in three populations from the Third National Health and Nutrition Examination Survey.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7767084
|overall_frequency_n=18
|overall_frequency_d=128
|overall_frequency=0.140625
|n_genomes=9
|n_genomes_annotated=0
|n_haplomes=11
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23653095
|Title=Positive correlation between variants of lipid metabolism‑related genes and coronary heart disease
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}