{{Rsnum
|rsid=7776054
|Chromosome=6
|position=135097778
|Orientation=plus
|GMAF=0.2466
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 64.1 | 28.1 | 7.8
| HCB | 53.3 | 35.6 | 11.1
| JPT | 40.0 | 48.9 | 11.1
| YRI | 58.7 | 33.3 | 7.9
| ASW | 0.0 | 0.0 | 0.0
| CHB | 53.3 | 35.6 | 11.1
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19862010
|Trait=Mean corpuscular hemoglobin
|Title=Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
|RiskAllele=G
|Pval=7E-69
|OR=0.01
|ORtxt=[0.009-0.0111] pg decrease
|OA=1
}}

{{PMID Auto
|PMID=18667698
|Title=DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.
|OA=1
}}

{{PMID Auto
|PMID=20401335
|Title=Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7776054
|overall_frequency_n=29
|overall_frequency_d=128
|overall_frequency=0.226562
|n_genomes=21
|n_genomes_annotated=0
|n_haplomes=23
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=23935956
  |Trait=Red blood cell traits
  |Title=Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.
  |RiskAllele=G
  |Pval=4E-6
  |OR=.01
  |ORtxt=[0.0060-0.0146] unit increase
  |OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}