{{Rsnum
|rsid=7784162
|Gene=NUP205
|Chromosome=7
|position=135621138
|Orientation=plus
|GMAF=0.2502
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=NUP205
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 6.2 | 33.6 | 60.2
| HCB | 7.3 | 32.8 | 59.9
| JPT | 8.0 | 44.2 | 47.8
| YRI | 8.8 | 39.5 | 51.7
| ASW | 14.0 | 42.1 | 43.9
| CHB | 7.3 | 32.8 | 59.9
| CHD | 8.3 | 39.4 | 52.3
| GIH | 8.9 | 48.5 | 42.6
| LWK | 9.1 | 49.1 | 41.8
| MEX | 6.9 | 34.5 | 58.6
| MKK | 7.7 | 33.5 | 58.7
| TSI | 3.9 | 32.4 | 63.7
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs7784162
|Name_s=
|Gene_s=NUP205
|Feature=
|Evidence=PubMed ID:17537913
|Annotation=Risk or phenotype-associated allele: not stated Phenotype: Using a Quantitative Transmission Disequilibrium Test (QTDT), this variant was significantly associated with etoposide toxicity based upon IC50 values in cell lines from 30 parent-child trios. Study size: 87. Study population/ethnicity: 87 European descent Caucasians. Significance metric(s): p = 0.00005. Type of association: FA; GN.
|Drugs=etoposide
|Drug Classes=
|Diseases=Drug Toxicity
|Curation Level=Curated
|PharmGKB Accession ID=PA165109442
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7784162
|overall_frequency_n=32
|overall_frequency_d=128
|overall_frequency=0.25
|n_genomes=24
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}