{{Rsnum
|rsid=7837688
|Chromosome=8
|position=127527115
|Orientation=plus
|GMAF=0.1097
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 85.0 | 14.2 | 0.9
| HCB | 71.1 | 25.9 | 3.0
| JPT | 68.8 | 27.7 | 3.6
| YRI | 87.6 | 11.7 | 0.7
| ASW | 94.7 | 5.3 | 0.0
| CHB | 71.1 | 25.9 | 3.0
| CHD | 76.1 | 19.3 | 4.6
| GIH | 73.0 | 24.0 | 3.0
| LWK | 82.6 | 16.5 | 0.9
| MEX | 87.9 | 12.1 | 0.0
| MKK | 85.1 | 14.3 | 0.6
| TSI | 85.3 | 13.7 | 1.0
| HapMapRevision=28
}}[[rs7837688]] is one of 4 tightly linked SNPs in the "locus 1" region of [[8q24]] chromosomal region, which has been linked in several studies to [[prostate cancer]], initially through [[rs1447295]].{{PMID|17925536}}

In a study of 1,563 patients of European ancestry, the odds ratio for [[prostate cancer]] associated with risk genotypes of locus 1 were reported as 1.70 (CI: 1.39-2.07). Two other regions of chromosome [[8q24]] were also studied.{{PMID|17925536}}

{{PMID Auto GWAS
|PMID=20676098
|Trait=None
|Title=Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population
|RiskAllele=
|Pval=1E-25
|OR=None
|ORtxt=None
}}

{{PMID Auto
|PMID=18231127
|Title=8q24 and prostate cancer: association with advanced disease and meta-analysis.
|OA=1
}}

{{PMID Auto
|PMID=18535017
|Title=Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.
|OA=1
}}

{{PMID Auto
|PMID=18704501
|Title=Comprehensive resequence analysis of a 136 kb region of human chromosome 8q24 associated with prostate and colon cancers.
|OA=1
}}

{{PMID Auto
|PMID=19528667
|Title=Association of chromosome 8q variants with prostate cancer risk in Caucasian and Hispanic men.
|OA=1
}}

{{PMID Auto
|PMID=21390317
|Title=Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.
|OA=1
}}

{{PMID Auto
|PMID=21455501
|Title=Genetic variants on chromosome 8q24 and colorectal neoplasia risk: a case-control study in China and a meta-analysis of the published literature.
|OA=1
}}

{{PMID Auto
|PMID=22382457
|Title=Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis.
|OA=1
}}

{{PMID Auto
|PMID=23532531
|Title=Common Variants at 8q24 are Associated with Prostate Cancer Risk in Serbian Population
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}