{{Rsnum
|rsid=7911129
|Gene=SMC3
|Chromosome=10
|position=112340871
|Orientation=plus
|GMAF=0.1152
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=132
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 92.9 | 7.1 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 40.1 | 47.6 | 12.2
| ASW | 42.9 | 37.5 | 19.6
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 93.1 | 6.9 | 0.0
| LWK | 32.7 | 47.3 | 20.0
| MEX | 84.5 | 15.5 | 0.0
| MKK | 41.0 | 46.8 | 12.2
| TSI | 96.1 | 3.9 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs7911129
|Name_s=
|Gene_s=SMC3
|Feature=
|Evidence=PubMed ID:19965390
|Annotation=Risk or phenotype-associated allele: A allele. Phenotype: Decreased fasting glucose. Study size: 4681. Study population/ethnicity: Replication study of Swedish control subjects. Significance metric(s): p = 0.02. Type of association: FA; GN.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus, Type 2
|Curation Level=Curated
|PharmGKB Accession ID=PA165291596
}}

{{PMID Auto
|PMID=17273969
|Title=Mutations in cohesin complex members SMC3 and SMC1A cause a mild variant of cornelia de Lange syndrome with predominant mental retardation.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7911129
|overall_frequency_n=17
|overall_frequency_d=128
|overall_frequency=0.132812
|n_genomes=12
|n_genomes_annotated=0
|n_haplomes=15
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Illumina Human 1M}}