{{Rsnum
|rsid=793862
|Gene=DCDC2
|Chromosome=6
|position=24206972
|Orientation=plus
|GMAF=0.4105
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=DCDC2
}}Rs793862, a SNP in the [[DCDC2]] gene, is in a region that crops up in several independent studies as likely to associated with [[dyslexia]]. The risk allele in the Caucasian populations studied is (A).

One study reports that the odds ratio for [[rs793862]] genotypes increases if calculated from subsets of more severely dyslexic individuals as compared to more heterogenous, larger groups of dyslexic individuals. The genotype relative risk (GRR) for [[rs793862(A;A)]] increased from 3.15 (95% CI 1.30-7.66; P=.011) for the larger group up to 5.40 (95% CI 1.27-23.01; P=.002) for the most severely affected group. {{PMID|16385449|OA=1
}}

Combined with another SNP marker in the [[DCDC2]] gene, [[rs807701]], the (haplotype) GRR also increased for the homozygous haplotype A-C, from 4.11 (95% CI 2.77-6.08; P<.0001) for the larger group, up to 11.13 (95% CI 6.32-19.60; P<.0001) for the most severely affected group. {{PMID|16385449|OA=1
}}

This SNP was also reported to be significantly associated in a linkage study of dyslexic individuals. {{PMID|15138886}}

{{PMID Auto
|PMID=15717286
|Title=Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia.
|OA=1
}}

{{PMID Auto
|PMID=19238550
|Title=The role of gene DCDC2 in German dyslexics.
}}

{{PMID Auto
|PMID=21881542
|Title=DCDC2 genetic variants and susceptibility to developmental dyslexia.
|OA=1
}}

{{PMID Auto
|PMID=25012462
|Title=The role of DCDC2 genetic variants and low socioeconomic status in vulnerability to attention problems
}}
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