{{Rsnum
|rsid=7953249
|Chromosome=12
|position=120965921
|Orientation=plus
|GMAF=0.427
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 27.4 | 51.3 | 21.2
| HCB | 30.7 | 51.1 | 18.2
| JPT | 9.7 | 61.1 | 29.2
| YRI | 51.7 | 38.8 | 9.5
| ASW | 45.6 | 47.4 | 7.0
| CHB | 30.7 | 51.1 | 18.2
| CHD | 36.1 | 48.1 | 15.7
| GIH | 20.8 | 46.5 | 32.7
| LWK | 40.9 | 50.0 | 9.1
| MEX | 43.1 | 41.4 | 15.5
| MKK | 16.0 | 50.0 | 34.0
| TSI | 31.4 | 49.0 | 19.6
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs7953249
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18439552
|Annotation=In a GWAS of subjects from the PARC study (Pharmacogenomics and Risk of Cardiovascular Disease), this was one of the ten SNPs most strongly associated with plasma C-reactive protein levels.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA162399731
}}

{{PMID Auto GWAS
|PMID=21203500
|Trait=None
|Title=Genomics Meets Glycomics-The First GWAS Study of Human N-Glycome Identifies HNF1± as a Master Regulator of Plasma Protein Fucosylation
|RiskAllele=G
|Pval=2E-8
|OR=0.1700
|ORtxt=[0.11-0.23] unit decrease
|OA=1
}}

{{PMID|18439548|OA=1
}} Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

{{PMID|18940312|OA=1
}} Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7953249
|overall_frequency_n=77
|overall_frequency_d=128
|overall_frequency=0.601562
|n_genomes=45
|n_genomes_annotated=0
|n_haplomes=67
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=23144326
  |Trait=Chronic obstructive pulmonary disease-related biomarkers
  |Title=Genome-Wide Association Analysis of Blood Biomarkers in Chronic Obstructive Pulmonary Disease.
  |RiskAllele=G
  |Pval=1E-6
  |OR=NR
  |ORtxt=NR
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}