{{Rsnum
|rsid=7958311
|Gene=P2RX7
|Chromosome=12
|position=121167552
|Orientation=plus
|GMAF=0.2893
|Gene_s=P2RX7
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 1.8 | 36.3 | 61.9
| HCB | 24.3 | 41.9 | 33.8
| JPT | 9.7 | 48.7 | 41.6
| YRI | 4.8 | 38.7 | 56.5
| ASW | 5.3 | 47.4 | 47.4
| CHB | 24.3 | 41.9 | 33.8
| CHD | 17.4 | 50.5 | 32.1
| GIH | 1.0 | 15.8 | 83.2
| LWK | 0.0 | 0.0 | 0.0
| MEX | 13.8 | 29.3 | 56.9
| MKK | 3.2 | 28.4 | 68.4
| TSI | 2.9 | 35.3 | 61.8
| HapMapRevision=28
}}{{PMID Auto
|PMID=22447075
|Title=Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity
|OA=1
}}

{{PMID Auto
|PMID=19319666
|Title=Genetics of the P2X7 receptor and human disease.
|OA=1
}}

{{PMID Auto
|PMID=19838818
|Title=Identification and characterization of a novel variant of the human P2X(7) receptor resulting in gain of function.
|OA=1
}}

{{GET Evidence
|gene=P2RX7
|aa_change=Arg270His
|aa_change_short=R270H
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs7958311
|overall_frequency_n=2638
|overall_frequency_d=10758
|overall_frequency=0.245213
|n_genomes=25
|n_genomes_annotated=0
|n_haplomes=27
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}