{{Rsnum
|rsid=80356666
|Chromosome=11
|Orientation=minus
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene=INS
|position=2160845
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=INS,INS-IGF2
}}{{omim
|id=176730
|rsnum=80356666
|variant=0009
}}{{ClinVar
|rsid=80356666
|Reversed=1
|FwdREF=T
|FwdALT=G
|REF=A
|ALT=C
|RSPOS=2182075
|CHROM=11
|dbSNPBuildID=132
|SSR=0
|SAO=1
|VP=0x050368000000000002110100
|GENEINFO=INS:3630; INS-IGF2:723961
|GENE_NAME=INS; INS-IGF2
|GENE_ID=3630; 723961
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000011.9:g.2182075A>C
|CLNSRC=GeneReviews; OMIM Allelic Variant; UniProtKB (variants)
|CLNORIGIN=0
|CLNSRCID=NBK1447; 176730.0009; VAR_063728
|CLNSIG=5
|CLNCUI=C1833104
|CLNDBN=Permanent neonatal diabetes mellitus; Neonatal diabetes mellitus
|Disease=Permanent neonatal diabetes mellitus; Neonatal diabetes mellitus
|CLNACC=RCV000020204.18; RCV000030069.1
|Tags=RV;PM;PMC;S3D;SLO;OTHERKG;LSD;OM
|CLNDSDB=GeneReviews:MedGen:OMIM:Orphanet:Orphanet; MedGen:SNOMED_CT
|CLNDSDBID=NBK1447:C1833104:606176:79134:99885; C0158981:49817004
}}{{PMID Auto
|PMID=17047922
|Title=Improved motor development and good long-term glycaemic control with sulfonylurea treatment in a patient with the syndrome of intermediate developmental delay, early-onset generalised epilepsy and neonatal diabetes associated with the V59M mutation in the KCNJ11 gene.
}}

{{PMID Auto
|PMID=18171712
|Title=Heterozygous missense mutations in the insulin gene are linked to permanent diabetes appearing in the neonatal period or in early infancy: a report from the French ND (Neonatal Diabetes) Study Group.
}}

{{PMID Auto
|PMID=17855560
|Title=Insulin gene mutations as a cause of permanent neonatal diabetes.
|OA=1
}}

{{PMID Auto
|PMID=20034
|Title=A long view of nitrogen metabolism.
}}

{{PMID Auto
|PMID=18162506
|Title=Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood.
}}

{{PMID Auto
|PMID=18436707
|Title=Neonatal diabetes mellitus.
|OA=1
}}

{{PMID Auto
|PMID=19817801
|Title=A brief perspective on insulin production.
}}

{{PMID Auto
|PMID=19952343
|Title=In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.
|OA=1
}}

{{PMID Auto
|PMID=20051530
|Title=Unfolding the mechanisms of disease progression in permanent neonatal diabetes.
}}