{{Rsnum
|rsid=80358241
|Chromosome=22
|Orientation=minus
|geno1=(-;-)
|geno2=(-;C)
|geno3=(C;C)
|Gene=MLC1
|position=50084767
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|Gene_s=MLC1
}}{{omim
|id=605908
|rsnum=80358241
|variant=0011
}}{{ClinVar
|rsid=80358241
|Reversed=1
|FwdREF=CTG
|FwdALT=C
|REF=A
|ALT=AG
|RSPOS=50523196
|CHROM=22
|dbSNPBuildID=132
|SSR=0
|SAO=1
|VP=0x050168000000000002110200
|GENEINFO=MLC1:23209
|GENE_NAME=MLC1
|GENE_ID=23209
|WGT=0
|VC=DIV
|CLNALLE=1
|CLNHGVS=NC_000022.10:g.50523196_50523197insG
|CLNSRC=GeneReviews; OMIM Allelic Variant
|CLNORIGIN=0
|CLNSRCID=NBK1535; 605908.0011
|CLNSIG=5
|CLNCUI=C1858854; C1858854
|CLNDBN=Megalencephalic leukoencephalopathy with subcortical cysts 1
|Disease=Megalencephalic leukoencephalopathy with subcortical cysts 1
|CLNACC=RCV000004987.2
|Tags=RV;PM;PMC;SLO;OTHERKG;LSD;OM
|CLNDSDB=GeneReviews:MedGen:OMIM:Orphanet
|CLNDSDBID=NBK1535:C1858854:604004:2478
}}{{PMID|11935341}} Identification of novel mutations in MLC1 responsible for megalencephalic leukoencephalopathy with subcortical cysts.

{{PMID|12189496}} Megalencephalic leukoencephalopathy with subcortical cysts; a founder effect in Israeli patients and a higher than expected carrier rate among Libyan Jews.