{{Rsnum
|rsid=80359675
|Orientation=plus
|Chromosome=13
|position=32331008
|geno1=(-;-)
|geno2=(-;TCAAA)
|geno3=(TCAAA;TCAAA)
|Gene=BRCA2
|Gene_s=BRCA2
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
}}[[rs80359675]], aka 999del5, represents a 5bp deletion in the [[BRCA2]] gene on chromosome 13. An alternative rs# for this same deletion is [[rs80359671]]. The BRCA2 999del5 deletion has been associated with significantly increased risk for [[breast cancer]] as well as some other cancers, at least in certain populations. For more information, see [http://omim.org/entry/600185#0010 OMIM 600185.0010].

{{ClinVar
|ALT=A
|CHROM=13
|CLNACC=RCV000009913.2; RCV000056288.3
|CLNALLE=1
|CLNDBN=Breast-ovarian cancer, familial 2; Familial cancer of breast
|CLNDSDB=GeneReviews:MedGen:OMIM:Orphanet; GeneReviews:MedGen:OMIM:SNOMED_CT
|CLNDSDBID=NBK1247:C2675520:612555:145; NBK1247:C0346153:114480:254843006
|CLNHGVS=NC_000013.10:g.32905145_32905149delTCAAA
|CLNSIG=255
|Disease=Breast-ovarian cancer; Familial cancer of breast
|FwdREF=TCAAA
|GENEINFO=BRCA2:675
|GENE_ID=675
|GENE_NAME=BRCA2
|REF=ATCAAA
|RSPOS=32905144
|Reversed=0
|SAO=0
|SSR=0
|Tags=PM;SLO;OTHERKG;LSD
|VC=DIV
|VP=0x050160000000000002100200
|WGT=0
|dbSNPBuildID=132
|rsid=80359675
|CLNSRC=GeneReviews; OMIM Allelic Variant
|CLNSRCID=NBK1247; 600185.0010
}}