{{Rsnum
|rsid=8040868
|Gene=CHRNA3
|Chromosome=15
|position=78618839
|Orientation=plus
|GMAF=0.3774
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CHRNA3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 17.7 | 51.3 | 31.0
| HCB | 4.4 | 51.8 | 43.8
| JPT | 12.4 | 47.8 | 39.8
| YRI | 11.6 | 46.9 | 41.5
| ASW | 15.8 | 45.6 | 38.6
| CHB | 4.4 | 51.8 | 43.8
| CHD | 6.4 | 55.0 | 38.5
| GIH | 6.9 | 32.7 | 60.4
| LWK | 16.4 | 44.5 | 39.1
| MEX | 5.2 | 43.1 | 51.7
| MKK | 17.9 | 48.7 | 33.3
| TSI | 22.5 | 48.0 | 29.4
| HapMapRevision=28
}}{{PMID Auto
|PMID=19859904
|Title=Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans
|OA=1
}}

{{PMID Auto
|PMID=22280835
|Title=New associations of the genetic polymorphisms in nicotinic receptor genes with the risk of lung cancer
|OA=1
}}

{{PMID Auto
|PMID=18163978
|Title=The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults.
|OA=1
}}

{{PMID Auto
|PMID=18165968
|Title=Identification of pharmacogenetic markers in smoking cessation therapy.
|OA=1
}}

{{PMID Auto
|PMID=19330903
|Title=Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.
|OA=1
}}

{{PMID Auto
|PMID=19443489
|Title=Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
|OA=1
}}

{{PMID Auto
|PMID=20808433
|Title=Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.
|OA=1
}}

{{PMID Auto
|PMID=22042234
|Title=Externalizing behaviors are associated with SNPs in the CHRNA5/CHRNA3/CHRNB4 gene cluster.
|OA=1
}}

{{PMID Auto
|PMID=23196875
|Title=Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder
|OA=1
}}

{{PMID Auto GWAS
  |PMID=23284291
  |Trait=Pulmonary function (interaction)
  |Title=Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
  |RiskAllele=T
  |Pval=9E-8
  |OR=NR
  |ORtxt=NR
  |OA=1
}}

{{PMID Auto
|PMID=22945651
|Title=Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}