{{Rsnum
|rsid=8055236
|Gene=CDH13
|Chromosome=16
|position=83178793
|Orientation=plus
|GMAF=0.2447
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=CDH13
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 63.7 | 33.6 | 2.7
| HCB | 75.7 | 22.8 | 1.5
| JPT | 72.3 | 26.8 | 0.9
| YRI | 19.2 | 46.6 | 34.2
| ASW | 24.6 | 45.6 | 29.8
| CHB | 75.7 | 22.8 | 1.5
| CHD | 82.4 | 15.7 | 1.9
| GIH | 66.3 | 29.7 | 4.0
| LWK | 18.3 | 49.5 | 32.1
| MEX | 73.7 | 26.3 | 0.0
| MKK | 16.0 | 57.7 | 26.3
| TSI | 61.8 | 32.4 | 5.9
| HapMapRevision=28
}}
[[rs8055236]] has been reported in a large study to be associated with [[heart disease]], in particular, [[coronary artery disease]].

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.91 (CI 1.33-2.74), and for homozygotes, 2.23 (CI 1.56-3.17). {{PMID|17554300|OA=1
}}

{{GWAS Summary
|SNP=rs8055236
|PubMedID=17554300
|Condition=Coronary disease
|Gene=NR
|Risk Allele=G
|pValue=6.00E-006
|OR=1.91
|95CI=1.33-2.74
|OA=1
}}

{{PharmGKB
|RSID=rs8055236
|Name_s=
|Gene_s=CDH13
|Feature=
|Evidence=PubMed ID:17554300; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS Results: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (Initial Sample Size: 1,926 cases, 2,938 controls; Replication Sample Size: (see Samani 2007); Risk Allele: rs8055236-G). This variant is associated with coronary disease.
|Drugs=
|Drug Classes=
|Diseases=Coronary Disease
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA162356658
}}

{{PMID Auto
|PMID=19956433
|Title=Genetics of coronary artery disease: focus on genome-wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=20017983
|Title=Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs8055236
|overall_frequency_n=44
|overall_frequency_d=128
|overall_frequency=0.34375
|n_genomes=30
|n_genomes_annotated=0
|n_haplomes=40
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}