{{Rsnum
|rsid=8176058
|Gene=KEL
|Chromosome=7
|position=142957921
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.01745
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=KEL
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 95.6 | 4.4 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 99.3 | 0.7 | 0.0
| ASW | 98.2 | 1.8 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 97.0 | 3.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 91.4 | 8.6 | 0.0
| MKK | 98.7 | 1.3 | 0.0
| TSI | 91.2 | 8.8 | 0.0
| HapMapRevision=28
}}{{omim
|desc=KELL K/k BLOOD GROUP POLYMORPHISM
|id=110900
|rsnum=8176058
|variant=0001
}}

{{ClinVar
|rsid=8176058
|Reversed=1
|FwdREF=C
|FwdALT=G,T
|REF=G
|ALT=A,C
|RSPOS=142655008
|CHROM=7
|GMAF=0.0174
|dbSNPBuildID=117
|SSR=0
|SAO=1
|VP=0x050368000000140517110100
|GENEINFO=KEL:3792
|GENE_NAME=KEL
|GENE_ID=3792
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000007.13:g.142655008G>A
|CLNSIG=2
|Tags=RV;PM;PMC;S3D;SLO;VLD;HD;GNO;KGPhase1;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.9826; 0.01745; .
|CLNACC=RCV000019295.1
|CLNDBN=KELL K/k BLOOD GROUP POLYMORPHISM
|CLNORIGIN=0
|CLNSRC=OMIM Allelic Variant
|CLNSRCID=613883.0001
|COMMON=1
|Disease=KELL K/k BLOOD GROUP POLYMORPHISM
}}

{{PMID|21257350|OA=1
}} DNA-based methods in the immunohematology reference laboratory.

{{PMID|7849312}} Molecular basis of the Kell (K1) phenotype.

{{GET Evidence
|gene=KEL
|aa_change=Thr193Met
|aa_change_short=T193M
|impact=benign
|qualified_impact=Low clinical importance, Uncertain benign
|inheritance=dominant
|quality_scores=Array
|dbsnp_id=rs8176058
|overall_frequency_n=345
|overall_frequency_d=10758
|overall_frequency=0.0320692
|n_genomes=5
|n_genomes_annotated=0
|n_haplomes=5
|n_articles=1
|n_articles_annotated=1
|qualityscore_in_vitro=1
|qualitycomment_in_vitro=Y
|qualityscore_case_control=5
|qualitycomment_case_control=Y
|qualityscore_familial=5
|qualitycomment_familial=Y
|qualityscore_severity=0
|qualityscore_treatability=2
|qualitycomment_treatability=Y
|in_omim=Y
|pph2_score=0.999
|nblosum100=2
|autoscore=4
|webscore=N
|n_web_uneval=9
|variant_evidence=0
|clinical_importance=0
|summary_short=This variant is also known as Kell or K1 or K (capitalized) in the Kell antigen system. K1-negative mothers (carrying no copies of this variant) carrying K1-positive fetuses (heterozygous or homozygous) are at risk for hemolytic disease of the newborn. About 9% of caucasians carry one or two copies of K1.
}}

[[Non-ABO Blood Groups]]

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}