{{Rsnum
|rsid=8176750
|Gene=ABO
|Chromosome=9
|position=133255672
|Orientation=minus
|ReferenceAllele=C
|GMAF=0.04867
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(-;-)
|geno2=(-;C)
|geno3=(C;C)
|Gene_s=ABO
}}This SNP is in the [[ABO]] gene, and is therefore potentially useful in determing blood group type, such as through the use of [[genosets]]. 

This particular SNP can be useful in determining whether an ABO type A allele is more specifically an A1 type allele or an A2 type allele.

The more common allele (80% of A types on average) is A1, consistent with having a [[rs8176750]](C) allele, with the rarer A2 allele encoded by the deletion form [[rs8176750]](-). This is the key defining characteristic between an A1 and an A2 allele.{{PMID|1520322}}

{{GET Evidence
|gene=ABO
|aa_change=Pro353Shift
|aa_change_short=P353Shift
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs8176750
|overall_frequency_n=1
|overall_frequency_d=122
|overall_frequency=0.00819672
|n_genomes=2
|n_genomes_annotated=0
|n_haplomes=2
|n_articles=0
|n_articles_annotated=0
|nblosum100=4
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}