{{Rsnum
|rsid=8176927
|Gene=DNASE1
|Chromosome=16
|position=3655379
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=T
|GMAF=0.02938
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=DNASE1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 99.1 | 0.9 | 0.0
| HCB | 99.3 | 0.7 | 0.0
| JPT | 98.2 | 1.8 | 0.0
| YRI | 77.6 | 21.1 | 1.4
| ASW | 73.2 | 26.8 | 0.0
| CHB | 99.3 | 0.7 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 93.0 | 7.0 | 0.0
| LWK | 82.6 | 16.5 | 0.9
| MEX | 96.5 | 3.5 | 0.0
| MKK | 79.5 | 19.9 | 0.6
| TSI | 99.0 | 1.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19360410
|Title=DNase1 exon2 analysis in Tunisian patients with rheumatoid arthritis, systemic lupus erythematosus and Sj&#xF6;gren syndrome and healthy subjects
}}

{{GET Evidence
|gene=DNASE1
|aa_change=Arg2Ser
|aa_change_short=R2S
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs8176927
|overall_frequency_n=426
|overall_frequency_d=10758
|overall_frequency=0.0395984
|n_genomes=4
|n_genomes_annotated=0
|n_haplomes=4
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.973
|nblosum100=3
|autoscore=3
|n_web_uneval=9
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}