{{Rsnum
|rsid=8178085
|Gene=PRKDC
|Chromosome=8
|position=47898144
|Orientation=minus
|GMAF=0.0326
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=PRKDC
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 100.0 | 0.0 | 0.0
| HCB | 84.7 | 15.3 | 0.0
| JPT | 91.1 | 8.9 | 0.0
| YRI | 91.0 | 9.0 | 0.0
| ASW | 93.0 | 7.0 | 0.0
| CHB | 84.7 | 15.3 | 0.0
| CHD | 84.4 | 13.8 | 1.8
| GIH | 99.0 | 1.0 | 0.0
| LWK | 86.4 | 13.6 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 93.5 | 6.5 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{PMID|18451257}} [[rs8178085]] and [[rs12334811]] with approaching dose-dependent effect on [[lung cancer]] predisposition, subjects carrying two to four risk genotypes were associated with a 43% decreased lung cancer risk compared with subjects carrying zero to one risk genotypes (adjusted odds ratio, 0.53; 95% confidence interval, 0.35-0.80).

[[rs228591]] variant allele or ataxia-telangiectasia and Rad3-related [[rs6782400]] wild-type homozygous genotype

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}