{{Rsnum
|rsid=8192708
|Gene=PCK1
|Chromosome=20
|position=57563565
|Orientation=plus
|GMAF=0.06795
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PCK1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 77.0 | 22.1 | 0.9
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 93.9 | 6.1 | 0.0
| ASW | 82.5 | 17.5 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 99.1 | 0.9 | 0.0
| GIH | 88.1 | 11.9 | 0.0
| LWK | 92.7 | 7.3 | 0.0
| MEX | 77.6 | 22.4 | 0.0
| MKK | 86.5 | 12.8 | 0.6
| TSI | 69.6 | 28.4 | 2.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=21152065
|Title=A Putative Alzheimer's Disease Risk Allele in PCK1 Influences Brain Atrophy in Multiple Sclerosis
|OA=1
}}

{{PMID Auto
|PMID=18780302
|Title=Association studies of 22 candidate SNPs with late-onset Alzheimer's disease.
|OA=1
}}

{{PMID Auto
|PMID=18813964
|Title=Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta.
|OA=1
}}

{{PMID Auto
|PMID=18830724
|Title=Assessment of Alzheimer's disease case-control associations using family-based methods.
|OA=1
}}

{{PMID Auto
|PMID=20574532
|Title=Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
|OA=1
}}

{{GET Evidence
|gene=PCK1
|aa_change=Ile267Val
|aa_change_short=I267V
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs8192708
|overall_frequency_n=1055
|overall_frequency_d=10758
|overall_frequency=0.0980666
|n_genomes=6
|n_genomes_annotated=0
|n_haplomes=6
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|pph2_score=0.167
|genetests_testable=Y
|nblosum100=-4
|autoscore=2
|n_web_uneval=2
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}