{{Rsnum
|rsid=8192709
|Gene=CYP2B6
|Chromosome=19
|position=40991369
|Orientation=plus
|GMAF=0.05326
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CYP2B6
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 92.8 | 7.2 | 0.0
| HCB | 94.8 | 5.2 | 0.0
| JPT | 88.5 | 9.7 | 1.8
| YRI | 92.2 | 7.1 | 0.7
| ASW | 91.1 | 8.9 | 0.0
| CHB | 94.8 | 5.2 | 0.0
| CHD | 92.5 | 7.5 | 0.0
| GIH | 94.1 | 5.0 | 1.0
| LWK | 84.8 | 14.3 | 1.0
| MEX | 96.6 | 3.4 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs8192709
|Name_s=CYP2B6:64C>T, CYP2B6*2,
|Gene_s=CYP2A7P1, CYP2B6
|Feature=
|Evidence=PubMed ID:19005482
|Annotation=Risk or phenotype-associated allele: T. Phenotype: CYP2B6*2 genotype in the transplant recipient was associated with hemorrhagic cystitis. Study size:107 . Study population/ethnicity: Donors and patients with leukemia after HLA-identical hematopoietic stem cell transplantation, France. Significance metric(s): p = 0.03. Type of association: TOX
|Drugs=cyclophosphamide
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA165282248
}}

{{PMID Auto
|PMID=21886015
|Title=Cytochrome P450 CYP2B6 genotypes and haplotypes in a Colombian population: identification of novel variant CYP2B6 alleles
}}

{{PMID Auto
|PMID=19076156
|Title=Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.
|OA=1
}}

{{GET Evidence
|gene=CYP2B6
|aa_change=Arg22Cys
|aa_change_short=R22C
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs8192709
|overall_frequency_n=512
|overall_frequency_d=10758
|overall_frequency=0.0475925
|n_genomes=5
|n_genomes_annotated=0
|n_haplomes=5
|n_articles=1
|n_articles_annotated=1
|in_pharmgkb=Y
|pph2_score=0.639
|nblosum100=8
|autoscore=3
|webscore=N
|n_web_uneval=10
}}

{{PMID Auto
|PMID=23133420
|Title=Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}