{{Rsnum
|rsid=8192917
|Gene=GZMB
|Chromosome=14
|position=24632954
|Orientation=minus
|GMAF=0.2851
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=GZMB
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 60.2 | 34.5 | 5.3
| HCB | 51.8 | 38.0 | 10.2
| JPT | 65.5 | 27.4 | 7.1
| YRI | 32.7 | 51.7 | 15.6
| ASW | 28.1 | 52.6 | 19.3
| CHB | 51.8 | 38.0 | 10.2
| CHD | 52.3 | 43.1 | 4.6
| GIH | 43.6 | 39.6 | 16.8
| LWK | 28.2 | 52.7 | 19.1
| MEX | 69.0 | 25.9 | 5.2
| MKK | 28.2 | 44.9 | 26.9
| TSI | 45.1 | 44.1 | 10.8
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=20410501
|Trait=Vitiligo
|Title=Variant of TYR and Autoimmunity Susceptibility Loci in Generalized Vitiligo
|RiskAllele=G
|Pval=3E-8
|OR=1.28
|ORtxt=[1.17-1.39]
|OA=1
}}

{{PMID Auto
|PMID=21886827
|Title=Genetic Variants of Human Granzyme B Predict Transplant Outcomes after HLA Matched Unrelated Bone Marrow Transplantation for Myeloid Malignancies
|OA=1
}}

{{PMID Auto
|PMID=18311812
|Title=Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis.
|OA=1
}}

{{GET Evidence
|gene=GZMB
|aa_change=Arg55Gln
|aa_change_short=R55Q
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs8192917
|overall_frequency_n=7556
|overall_frequency_d=10758
|overall_frequency=0.702361
|n_genomes=51
|n_genomes_annotated=0
|n_haplomes=83
|n_articles=0
|n_articles_annotated=0
|nblosum100=0
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23528102
|Title=Association between granzyme B and perforin I polymorphisms and allograft outcomes in Hispanic kidney transplant recipients
}}

{{PMID Auto
|PMID=23321921
|Title=Risk of generalized vitiligo is associated with the common 55R-94A-247H variant haplotype of GZMB (encoding granzyme B).
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}