{{Rsnum
|rsid=828907
|Gene=XRCC5
|Chromosome=2
|position=216108009
|Orientation=plus
|GMAF=0.2957
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=XRCC5
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 28.3 | 47.8 | 23.9
| HCB | 64.2 | 32.1 | 3.6
| JPT | 61.9 | 30.1 | 8.0
| YRI | 66.7 | 31.3 | 2.0
| ASW | 64.9 | 31.6 | 3.5
| CHB | 64.2 | 32.1 | 3.6
| CHD | 67.0 | 29.4 | 3.7
| GIH | 18.8 | 46.5 | 34.7
| LWK | 75.2 | 22.0 | 2.8
| MEX | 58.6 | 22.4 | 19.0
| MKK | 55.1 | 41.0 | 3.8
| TSI | 37.3 | 48.0 | 14.7
| HapMapRevision=28
}}[[rs828907]], also known as G-1401T, is a SNP in the Ku80 gene.

A study of 288 Chinese patients with [[bladder cancer]] and 288 age- and gender-matched healthy controls found that the [[rs828907]](T) allele conferred a significant (p=0.0055) increased risk of bladder cancer. In association with smoking, the (G;T) and (T;T) genotypes conferred a 2x risk (CI:1.232-3.419) for bladder cancer.{{PMID|19414375}}

{{PMID|19217823}} correlated with oral cancer susceptibility

{{PMID Auto
|PMID=19528488
|Title=Significant Association of Ku80 Single Nucleotide Polymorphisms with Colorectal Cancer Susceptibility in Central Taiwan
}}

{{PMID Auto
|PMID=20044645
|Title=Significant Association of DNA Repair Gene Ku80 Genotypes with Breast Cancer Susceptibility in Taiwan
}}

{{PMID Auto
|PMID=23098447
|Title=Association between XRCC5, 6 and 7 gene polymorphisms and the risk of breast cancer: a HuGE review and meta-analysis
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}