{{Rsnum
|rsid=8321
|Gene=ZNRD1
|Chromosome=6
|position=30064745
|Orientation=minus
|GMAF=0.0326
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=PPP1R11,ZNRD1
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 0.9 | 19.5 | 79.6
| HCB | 0.0 | 0.0 | 100.0
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.0 | 0.0 | 100.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 0.0 | 0.0 | 100.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 3.4 | 96.6
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 9.8 | 90.2
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19115949
|Trait=AIDS progression
|Title=Genomewide Association Study of an AIDS-Nonprogression Cohort Emphasizes the Role Played by HLA Genes (ANRS Genomewide Association Study 02).
|RiskAllele=G
|Pval=5E-7
|OR=NR
|ORtxt=NR
}}

{{PharmGKB
|RSID=rs8321
|Name_s=
|Gene_s=PPP1R11, ZNRD1
|Feature=
|Evidence=PubMed ID:19115949; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genomewide Association Study of an AIDS-Nonprogression Cohort Emphasizes the Role Played by HLA Genes (ANRS Genomewide Association Study 02).. (Initial Sample Size: 275 HIV positive patients, 1,438 controls; Replication Sample Size: 626 patients); (Region: 6p21.33; Reported Gene(s): ZNRD1, RNF39; Risk Allele: rs8321-G); (p-value= 0.0000005).This variant is associated with AIDS progression.
|Drugs=
|Drug Classes=
|Diseases=Acquired Immunodeficiency Syndrome
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740095
}}

{{PMID|21221856|OA=1
}} The search for host genetic factors of HIV/AIDS pathogenesis in the post-genome era: progress to date and new avenues for discovery.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs8321
|overall_frequency_n=494
|overall_frequency_d=7520
|overall_frequency=0.0656915
|n_genomes=4
|n_genomes_annotated=0
|n_haplomes=4
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto GWAS
  |PMID=23453885
  |Trait=Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined)
  |Title=Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
  |RiskAllele=
  |Pval=8E-9
  |OR=1.08
  |ORtxt=[1.04-1.12]
  |OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}