{{Rsnum
|rsid=846111
|Gene=RNF207
|Chromosome=1
|position=6219310
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=C
|GMAF=0.174
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=RNF207
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 50.8 | 38.5 | 10.8
| HCB | 68.9 | 31.1 | 0.0
| JPT | 68.2 | 22.7 | 9.1
| YRI | 96.8 | 3.2 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 68.9 | 31.1 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}[http://blog.23andme.com/2009/03/23/snpwatch-researchers-identify-genetic-variants-linked-to-heart-rhythm-and-possibly-sudden-cardiac-death/ 23andMe blog] Influences [[QT interval]]

{{PMID Auto GWAS
|PMID=19305408
|Trait=QT interval
|Title=Common variants at ten loci influence QT interval duation in the QTGEN Study
|RiskAllele=C
|Pval=1E-16
|OR=1.75
|ORtxt=[1.41-2.09] msec increase
|OA=1
}}
{{PMID Auto GWAS
|PMID=19305409
|Trait=QT interval
|Title=Common variants at ten loci modulate the QT interval duration in the QTSCD Study
|RiskAllele=C
|Pval=4E-16
|OR=1.49
|ORtxt=[1.00-1.98] ms increase
|OA=1
}}

{{PharmGKB
|RSID=rs846111
|Name_s=
|Gene_s=ICMT
|Feature=
|Evidence=PubMed ID:19305409; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common variants at ten loci modulate the QT interval duration in the QTSCD Study. (Initial Sample Size: 15,842 individuals; Replication Sample Size: up to 13,602 individuals); (Region: 1p36.31; Reported Gene(s): RNF207; Risk Allele: rs846111-C); (p-value= 0.0000000000000004).This variant is associated with QT interval.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739899
}}

{{PharmGKB
|RSID=rs846111
|Name_s=
|Gene_s=ICMT
|Feature=
|Evidence=PubMed ID:19305408; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Common variants at ten loci influence QT interval duation in the QTGEN Study. (Initial Sample Size: 13,685 individuals; Replication Sample Size: 15,854 individuals); (Region: 1p36.31; Reported Gene(s): RNF207,NPHP4, CHDS, ACOT7, PLEKHG5, KLH21; Risk Allele: rs846111-C); (p-value= 0.0000000000000001).This variant is associated with QT interval.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739897
}}

{{GET Evidence
|gene=RNF207
|aa_change=Gly603Ala
|aa_change_short=G603A
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs846111
|overall_frequency_n=1919
|overall_frequency_d=9656
|overall_frequency=0.198737
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|pph2_score=0.006
|nblosum100=1
|autoscore=2
|webscore=N
}}

{{on chip | HumanOmni1Quad}}