{{Rsnum
|rsid=852977
|Gene=NR3C1
|Chromosome=5
|position=143307929
|Orientation=plus
|GMAF=0.2576
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=NR3C1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 45.1 | 43.4 | 11.5
| HCB | 81.0 | 17.5 | 1.5
| JPT | 83.2 | 16.8 | 0.0
| YRI | 51.7 | 36.7 | 11.6
| ASW | 38.6 | 50.9 | 10.5
| CHB | 81.0 | 17.5 | 1.5
| CHD | 76.1 | 21.1 | 2.8
| GIH | 65.3 | 30.7 | 4.0
| LWK | 41.8 | 44.5 | 13.6
| MEX | 67.2 | 27.6 | 5.2
| MKK | 48.7 | 41.0 | 10.3
| TSI | 40.2 | 47.1 | 12.7
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs852977
|Name_s=
|Gene_s=NR3C1
|Feature=Intron
|Evidence=PubMed ID:19365399
|Annotation=This variant is associated with response to escitalopram and nortriptyline in a study of 760 adult patients with moderate-to-severe depression.
|Drugs=escitalopram; nortriptyline
|Drug Classes=
|Diseases=Depression
|Curation Level=Curated
|PharmGKB Accession ID=PA164924622
}}

{{PMID|18504423|OA=1
}} Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response.

{{PMID|19772600|OA=1
}} A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs852977
|overall_frequency_n=28
|overall_frequency_d=126
|overall_frequency=0.222222
|n_genomes=22
|n_genomes_annotated=0
|n_haplomes=24
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}