{{Rsnum
|rsid=880395
|Chromosome=15
|position=78552014
|Orientation=plus
|GMAF=0.2489
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 20.0 | 36.9 | 43.1
| HCB | 6.7 | 22.2 | 71.1
| JPT | 2.3 | 13.6 | 84.1
| YRI | 1.6 | 31.7 | 66.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 6.7 | 22.2 | 71.1
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=20700147
|Title=Nicotinic alpha5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms
|OA=1
}}{{PMID|18519524|OA=1
}} Variants in nicotinic receptors and risk for nicotine dependence.

{{PMID|19443489|OA=1
}} Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.