{{Rsnum
|rsid=884205
|Gene=TNFRSF11A
|Chromosome=18
|position=62387624
|Orientation=minus
|GMAF=0.1882
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=TNFRSF11A
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 51.3 | 41.6 | 7.1
| HCB | 62.8 | 32.1 | 5.1
| JPT | 57.5 | 35.4 | 7.1
| YRI | 91.8 | 8.2 | 0.0
| ASW | 89.5 | 8.8 | 1.8
| CHB | 62.8 | 32.1 | 5.1
| CHD | 69.7 | 25.7 | 4.6
| GIH | 55.4 | 35.6 | 8.9
| LWK | 96.4 | 3.6 | 0.0
| MEX | 63.8 | 34.5 | 1.7
| MKK | 88.5 | 11.5 | 0.0
| TSI | 66.7 | 30.4 | 2.9
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19801982
|Trait=Bone mineral density (spine)
|Title=Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
|RiskAllele=A
|Pval=9E-9
|OR=0.08
|ORtxt=[0.05-0.11] sd decrease
|OA=1
}}

{{PMID Auto
|PMID=22370887
|Title=Are bone mineral density loci associated with hip osteoporotic fractures? A validation study on previously reported genome-wide association loci in a Chinese population
|OA=1
}}

{{PMID Auto
|PMID=16960694
|Title=Is a gene important for bone resorption a candidate for obesity? An association and linkage study on the RANK (receptor activator of nuclear factor-kappaB) gene in a large Caucasian sample.
|OA=1
}}

{{PMID Auto
|PMID=17002564
|Title=Robust and comprehensive analysis of 20 osteoporosis candidate genes by very high-density single-nucleotide polymorphism screen among 405 white nuclear families identified significant association and gene-gene interaction.
|OA=1
}}

{{PMID Auto
|PMID=18466469
|Title=Genome-wide analysis of single-locus and epistasis single-nucleotide polymorphism effects on anti-cyclic citrullinated peptide as a measure of rheumatoid arthritis.
|OA=1
}}

{{PMID Auto
|PMID=19458885
|Title=Association analyses of RANKL/RANK/OPG gene polymorphisms with femoral neck compression strength index variation in Caucasians.
|OA=1
}}

{{PMID Auto GWAS
|PMID=22504420
|Trait=None
|Title=Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
|RiskAllele=A
|Pval=2E-17
|OR=0.0500
|ORtxt=None
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs884205
|overall_frequency_n=112
|overall_frequency_d=126
|overall_frequency=0.888889
|n_genomes=52
|n_genomes_annotated=0
|n_haplomes=97
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}