{{Rsnum
|rsid=890293
|Gene=CYP2J2
|Chromosome=1
|position=59926822
|Orientation=plus
|GMAF=0.07346
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=CYP2J2
}}[http://www.pharmgkb.org/search/annotatedGene/cyp2j2/variant.jsp Important Variant Information for CYP2J2]. involved in metabolism of some drugs.

[[rs890293]], also known as -50C>T, is a SNP in the [[CYP2J2]] gene.

A study of 5,740 participants of the cardiovascular cohort of the 'Malmö Diet and Cancer' study was monitored for cardiovascular events over 10 years, with the conclusion being there was no significant association between this SNP and either hypertension or ischemic events.{{PMID|19851119}}

{{PharmGKB
|RSID=rs890293
|Name_s=CYP2J2*7, CYP2J2:G-50T, CYP2J2:G-76T
|Gene_s=CYP2J2
|Feature=
|Evidence=Web Resource:http://www.pharmgkb.org/search/annotatedGene/cyp2j2/variant.jsp
|Annotation=Although this promoter SNP is the most-studied CYP2J2 variant, its in vivo effects remain unclear due to conflicting experimental findings.
|Drugs=astemizole; diclofenac; terfenadine
|Drug Classes=
|Diseases=Asthma; Brain Ischemia; Coronary Artery Disease; Coronary Disease; Coronary Stenosis; Essential hypertension; Hypertension
|Curation Level=In-Depth
|PharmGKB Accession ID=PA162355807
}}

{{PMID Auto
|PMID=20140850
|Title=Genetic Variation in the G-50T Polymorphism of the Cytochrome P450 Epoxygenase CYP2J2 Gene and the Risk of Younger Onset Type 2 Diabetes among Chinese Population: Potential Interaction with Body Mass Index and Family History
}}

{{PMID Auto
|PMID=18769365
|Title=Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs890293
|overall_frequency_n=7
|overall_frequency_d=84
|overall_frequency=0.0833333
|n_genomes=4
|n_genomes_annotated=0
|n_haplomes=4
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=10
}}

{{PMID Auto
|PMID=23684773
|Title=A Novel Polymorphism of the CYP2J2 Gene is Associated with Coronary Artery Disease in Uygur Population in China
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}