{{Rsnum
|rsid=9001
|Gene=CHDH
|Chromosome=3
|position=53823890
|Orientation=minus
|GMAF=0.2461
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=CHDH
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 84.1 | 15.0 | 0.9
| HCB | 46.3 | 40.4 | 13.2
| JPT | 31.2 | 50.0 | 18.8
| YRI | 41.0 | 49.3 | 9.7
| ASW | 49.1 | 45.6 | 5.3
| CHB | 46.3 | 40.4 | 13.2
| CHD | 38.0 | 46.3 | 15.7
| GIH | 77.2 | 20.8 | 2.0
| LWK | 47.3 | 44.5 | 8.2
| MEX | 69.0 | 27.6 | 3.4
| MKK | 0.0 | 0.0 | 0.0
| TSI | 78.4 | 21.6 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=18682255
|Title=Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions
}}

{{PMID Auto
|PMID=16816108
|Title=Common genetic polymorphisms affect the human requirement for the nutrient choline.
|OA=1
}}

{{PMID Auto
|PMID=17613168
|Title=Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline.
|OA=1
}}

{{PMID Auto
|PMID=17616785
|Title=Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not.
|OA=1
}}

{{PMID Auto
|PMID=18230680
|Title=Choline metabolism and risk of breast cancer in a population-based study.
|OA=1
}}

{{PMID Auto
|PMID=18789905
|Title=Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models.
|OA=1
}}

{{PMID Auto
|PMID=19116320
|Title=Importance of methyl donors during reproduction.
|OA=1
}}

{{PMID Auto
|PMID=19261726
|Title=Epigenetic mechanisms for nutrition determinants of later health outcomes.
|OA=1
}}

{{GET Evidence
|gene=CHDH
|aa_change=Glu40Ala
|aa_change_short=E40A
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs9001
|overall_frequency_n=1126
|overall_frequency_d=9330
|overall_frequency=0.120686
|n_genomes=18
|n_genomes_annotated=0
|n_haplomes=23
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.47
|nblosum100=3
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}