{{Rsnum
|rsid=907715
|Gene=IL21
|Chromosome=4
|position=122613898
|Orientation=minus
|GMAF=0.3664
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=IL21
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 8.8 | 40.7 | 50.4
| HCB | 28.0 | 45.5 | 26.5
| JPT | 27.9 | 52.3 | 19.8
| YRI | 14.6 | 50.7 | 34.7
| ASW | 10.7 | 48.2 | 41.1
| CHB | 28.0 | 45.5 | 26.5
| CHD | 21.1 | 45.0 | 33.9
| GIH | 5.0 | 47.0 | 48.0
| LWK | 10.9 | 41.8 | 47.3
| MEX | 10.5 | 43.9 | 45.6
| MKK | 11.0 | 41.6 | 47.4
| TSI | 10.8 | 51.0 | 38.2
| HapMapRevision=28
}}

{{PMID|20553587|OA=1
}} Confirmation of association of [[rs6822844]] with rheumatoid arthritis at a genome-wide level of significance

{{PMID Auto
|PMID=17720724
|Title=Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.
}}

{{PMID Auto
|PMID=19644854
|Title=A polymorphism within IL21R confers risk for systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=20652041
|Title=Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=21425124
|Title=Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
|OA=1
}}

{{PMID Auto
|PMID=23172754
|Title=Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility
}}

{{PMID Auto
|PMID=23354321
|Title=IL21 and IL21R polymorphisms and their interactive effects on serum IL-21 and IgE levels in patients with chronic hepatitis B virus infection
}}

{{PMID Auto
|PMID=24389496
|Title=Interleukin (IL)-21 promoter polymorphism increases the risk of thyroid cancer in Chinese population
}}

{{PMID Auto
|PMID=24434811
|Title=The association of Interleukin-21 polymorphisms with Interleukin-21 serum levels and risk of systemic lupus erythematosus
}}

{{PMID Auto
|PMID=22752563
|Title=A single nucleotide polymorphism of IL-21 gene is associated with systemic lupus erythematosus in a Chinese population.
}}

{{PMID Auto
|PMID=23288348
|Title=IL-21 gene polymorphism is associated with the prognosis of breast cancer in Chinese populations.
}}

{{PMID Auto
|PMID=24879484
|Title=Interleukin-21 Polymorphism Affects Gene Expression and is Associated with Risk of Ischemic Stroke
}}

{{PMID Auto
|PMID=25074442
|Title=Association of IL-21 polymorphisms (rs907715, rs2221903) with susceptibility to multiple autoimmune diseases: A meta-analysis
}}
{{on chip | Illumina Human 1M}}